Europa Press <- - google_ad_section_end (name = noticia_titulo)!> | 19/11/2014 – 21:19
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An international research consortium involving the Centre for Genomic Regulation (CRG) has validated the usefulness of mice for testing new therapies and drugs, considering that look similar to the human genome.
The validation result of a study published in the journal Nature, is based on A comprehensive description of the functional elements of the genome of mice and comparison with the human genome, reported Wednesday the CRG in a statement.
The mouse is one of the most used animal models to study human biology and is used to create models of human diseases and test new drugs and therapies, has highlighted one of the principal investigators of the study and coordinator of Bioinformatics and Genomics program at CRG, Roderic Guigó.
The study validates in much of the utility of this animal model and offers a “tremendous support” for use in human disease because they found that many cellular processes are highly conserved in both species, such as in embryonic development.
“Knowing these similarities will allow more precise studies of human biology,” said Guigó, which specified that the international work has discovered the keys that could explain why some processes and systems in mice, as the immune system, metabolism and stress response, are so different when it comes to humans. DATA FOR SCIENTISTS
Scientists have detailed functional parts of the mouse genome and compared with those of humans: it has resulted in a set of data-now available to the community that scientifically will be relevant to the investigation in mammalian biology, and for studying the mechanisms of human diseases.
The results of this comparison examines the genetic and biochemical processes that regulate genome activity in humans and mice, and find that, in general, the systems used to monitor the activity of the genome are very similar in both species have been preserved over time
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