(Reuters Health) – A new method of 3D printing produces bones, muscles and cartilage of human size that survive when implanted in animals, as published by a team of United States.
“It was a challenge to produce tissue on a human scale with 3D printing because the longer fabrics require extra nutrition,” said Dr. Anthony Atala, of the Faculty of Medicine of Wake Forest, Winston Salem, North Carolina.
his team developed a process called or ITOP, for its acronym in English, which creates a network of tiny channels to nourish printed fabrics “integrated printing system tissues and organs” after implantation into a living animal.
researchers printed three types of tissue, bone, cartilage and muscle, transplanted into rats and mice. At five months, the bone tissue was similar to normal bone, blood vessels and no dead areas, as published by the researchers in the journal Nature Biotechnology.
In a microscope, the human ear implants size they look like normal cartilage, with blood vessels that nourish the outer regions without circulation in the inner regions (such as natural cartilage). The fact that there were viable cells in the inner regions of the implant suggests that receive adequate nutrition.
The results with printed skeletal muscle are impressive. Not only because the implants are similar to normal muscle two weeks after transplantation, but also because contract as the immature developing tissue when it is stimulated.
“It is often frustrating for doctors place a plastic or metal implant during surgery when the best replacement would be the patient’s own tissue, “Atala said.
“The results of this study bring us closer to that reality with the use of 3D printing to repair defects by engineering custom fabrics. We are also applying similar strategies to print solid bodies.”
LOBAT Tayebi, Faculty of Dentistry, Marquette University, Milwaukee, Wisconsin, and it investigates the bioimpresión, said “there are many difficulties with bioimpresos tissues in terms of robustness, integrity and (blood nutrition) of the final product .
“the most admirable of this study is the serious effort to overcome these problems with the ITOP. It is a breakthrough in the production of robust bioprosthetic tissue of any size and shape. Although it is an approach with great difficulty, could it be applied in the production of reliable and robust bioimpresos tissues, “he said.
” The personalized medicine in the field of tissue regeneration is underway, “he added.
Source: Nature Biotechnology, online February 15, 2016
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